Study identifies constellation of metabolites linked to ME/CFS

A study led by researchers at the Center for Infection and Immunity (CII) at Columbia University’s Mailman School of Public Health has identified a constellation of metabolites related to myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Combining this data with data from an earlier microbiome study, the researchers now report they can predict whether or not someone […]

New TSPO-targeted PET imaging more fully evaluates extent of rheumatoid arthritis

A new positron emission tomography (PET) imaging method more fully evaluates the extent of rheumatoid arthritis by targeting translocator protein (TSPO) expression in the synovium (joint lining tissue). The study is featured in the July issue of The Journal of Nuclear Medicine. PET radioligands that target TSPO, which is highly expressed on activated macrophages (immune […]

Novel plasmonic patch increases brightness in diagnostic tests

Fluorescence-based biosensing and bioimaging technologies are widely used in research and clinical settings to detect and image various biological species of interest. While fluorescence-based detection and imaging techniques are convenient to use, they suffer from poor sensitivity. For example, when a patient carries low levels of antigens in the blood or urine, the fluorescent signal […]

Mice study shows promise for treating genetic conditions during fetal development

Researchers at Carnegie Mellon University and Yale University have for the first time used a gene editing technique to successfully cure a genetic condition in a mouse model. Their findings, published in Nature Communications, present a promising new avenue for research into treating genetic conditions during fetal development. An estimated 8 million children are born […]