Leading genetics study method may need reconsideration, significant distortions discovered

Many conclusions drawn from a common approach to the study of human genetics could be distorted because of a previously overlooked phenomenon, according to researchers at the Department of Genetics and Genomics Sciences at the Icahn School of Medicine at Mount Sinai and collaborators from Massachusetts General Hospital and the Broad Institute. Their conclusions and […]

In Huntington’s disease, heart problems reflect broader effects of abnormal protein

Researchers investigating a key signaling protein in Huntington’s disease describe deleterious effects on heart function, going beyond the disease’s devastating neurological impact. By adjusting protein levels affecting an important biological pathway, the researchers improved heart function in experimental animals, shedding light on the biology of this fatal disease. “Heart disease is the second leading cause […]

High immune function tied to stunted growth

Elevated immune function during childhood results in as much as 49 percent growth reduction in Ecuador’s indigenous Shuar population, researchers reported in the Proceedings of the National Academy of Sciences. Immune function protects the body from foreign bacteria, viruses and other substances. However, it is metabolically expensive and may divert calories away from other important […]

Researchers develop low-cost, portable laboratory on a phone to detect infections

Washington State University researchers have developed a low-cost, portable laboratory on a phone that works nearly as well as clinical laboratories to detect common viral and bacterial infections. The work could lead to faster and lower-cost lab results for fast-moving viral and bacterial epidemics, especially in rural or lower-resource regions where laboratory equipment and medical […]

What is Crouzon syndrome?

What are the symptoms? Complications Causes Genes Diagnosis Treatment options Prevention Takeaway Crouzon syndrome is a rare genetic condition that affects the shape of the head and face. In Crouzon syndrome, certain bones in the skull fuse too soon. This process is called craniosynostosis. There are other effects of this condition and ways to manage […]