New optogenetic tools show promise in treating cardiovascular, neuropsychiatric disorders

You’ve heard of “nature versus nurture,” and philosophers argue about which is more important. But how does this work on the cellular level? Although genes stay the same throughout the lifespan, genetic code isn’t necessarily a person’s destiny. In fact, genes can be switched on and off to regulate a number of activities within cells. […]

Antidepressants and bladder medicines linked to dementia in landmark study

Long-term use of some anticholinergic medications are associated with an increased risk of dementia — according to a new study led by the University of East Anglia (UK). Anticholinergic antidepressants have been found to be linked with dementia, even when taken up to 20 years before a diagnosis. Examples of frequently-prescribed anticholinergic antidepressants include Amitriptyline, […]

Targeting telomerase as therapeutic strategy for melanoma

Targeting telomerase was effective at killing NRAS-mutant melanoma cells, and the impact was further enhanced when the strategy was paired with an inhibitor of mitochondrial function, according to study results by The Wistar Institute published in Oncogene. “Many melanoma patients do not benefit from new treatment options or experience disease progression because of resistance. Our […]

Researchers recommend anti-cancer immunotherapies for treatment of thyroid cancer

University of Colorado Cancer Center researchers recently completed the largest-ever study of thyroid cancer genetics, mining the data of 583 patient samples of advanced differentiated thyroid cancer and 196 anaplastic thyroid cancers. In addition to identification of specific genes that may drive these cancers and thus provide attractive targets for treatment, the researchers found that […]

Blood biopsies may offer more comprehensive genetic information than bone marrow tests, shows research

Bone marrow biopsies are the gold standard for diagnosing and monitoring the progression of multiple myeloma, but these procedures are far too invasive to perform at every patient visit. Scientists from the Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard, however, have shown that two ways to measure multiple myeloma DNA in […]

Transplants of stem cells derived from your own fat or marrow, and platelet rich plasma to stimulate healing and repair injuries to bones and cartilage caused by injuries or diseases, such as osteoarthritis: are the tools of the bio-orthopaedics, which has become more widespread Over 15 years in Italy, the number of orthopedic that will […]