Bipolar and schizophrenia symptoms

Related video Symptoms of bipolar disorder Symptoms of mania Symptoms of depression Symptoms of schizophrenia Delusions Hallucinations Disorganized thinking and speech Abnormal behavior Inability to function regularly Overlapping symptoms Psychotic episodes Disorganized thinking Symptoms of depression Substance use disorders Prevalence Diagnosis A physical examination A psychological evaluation Diary of symptoms and moods Treatment Treatment for […]

Excess immune pruning of synapses in neural cells derived from patients with schizophrenia

Related video A study led by Massachusetts General Hospital (MGH) investigators finds evidence that the process of synaptic pruning, a normal part of brain development during adolescence, is excessive in individuals with schizophrenia. While previous studies have found structural abnormalities in the brains of people with schizophrenia that suggested a role for abnormal synaptic pruning, […]

Researchers identify treatable mechanism in patients with schizophrenia

Related video Increased degradation of synapse Antibiotic proved to inhibit the synaptic pruning For reasons that are unclear, schizophrenia patients have fewer connections between the neurons in the brain. Researchers at Karolinska Institutet, Sweden, and Massachusetts General Hospital, USA, have now succeeded in creating human cell models that show that there is an excessive degradation […]

Copy number variants linked with ‘schizophrenia-like’ subtype of bipolar disorder

Related video A genome-wide association study in Biological Psychiatry examines the role of copy number variants in subtypes of bipolar disorder A form of rare genomic structural variation called copy number variants (CNVs) may be more closely associated with schizophrenia than bipolar disorder. A new study published in Biological Psychiatry failed to find that CNVs […]

Copy number variants contribute to risk of ‘schizophrenia-like’ bipolar disorder subtype

Related video A form of rare genomic structural variation called copy number variants (CNVs) may be more closely associated with schizophrenia than bipolar disorder. A new study published in Biological Psychiatry failed to find that CNVs were associated broadly with risk for bipolar disorder. However, schizoaffective disorder, which is a hybrid of bipolar disorder and […]

Genetic variants implicated in development of schizophrenia

Related video Genetic variants which prevent a neurotransmitter receptor from working properly have been implicated in the development of schizophrenia, according to research by the UCL Genetics Institute. The N-methyl-D-aspartate receptor (NMDAR) is a protein which normally carries signals between brain cells in response to a neurotransmitter called glutamate. Previous research has shown that symptoms […]

Outdated commissioning methods are failing mental health services in the UK, reveals report

Related video A new report published today by the Janssen Pharmaceutical Companies of Johnson & Johnson highlights that mental health services in the UK are falling behind physical health services, due to healthcare providers using outdated commissioning methods. The report brings to light challenges faced by the UK’s pressurized mental health sector, with a specific […]

Have researchers found a new risk factor for schizophrenia?

Related video A link between schizophrenia and infection? ‘Unusal response to Epstein-Barr virus’ Scientists have located an intriguing link between schizophrenia and the Epstein-Barr virus, a type of herpes virus. Now, they need to determine which way the risk lies. A new study may have found another environmental risk factor linked to schizophrenia. Schizophrenia, a […]

Schizophrenia patients have higher levels of antibodies against Epstein-Barr virus, study shows

Related video New research from Johns Hopkins Medicine and Sheppard Pratt Health System shows that people in the study with schizophrenia also have higher levels of antibodies against the Epstein-Barr virus (EBV), a herpes virus that causes infectious mononucleosis, so-called mono. Researchers proposed two explanations for the association of heightened immune responses in patients with […]