Mechanism of fibrosis development discovered

These are extracellular vesicles under the electron microscope Credit: Helmholtz Zentrum München These are extracellular vesicles under the electron microscope Credit: Helmholtz Zentrum München Close Idiopathic pulmonary fibrosis (IPF) is an incurable lung disease of unknown origin with limited treatment options. Research suggests that the signaling molecule WNT5A plays a key role in the pathogenic […]

Single transplantation of therapeutic macrophages improves rare lung disease in mice

Hereditary pulmonary alveolar proteinosis (herPAP) is a rare disease characterized by the slow build-up of lipo-protein material in the lungs due to the failure of highly specialized cells called macrophages, which usually eat away this material from the pulmonary air-space. On August 9 in the journal Stem Cell Reports, researchers in Germany demonstrate that a […]

Researchers success in transplanting bioengineered human lungs into pigs

Researchers have successfully transplanted bioengineered lungs into pigs, without any complications arising. © crystal light/Shutterstock.com In 2014, Joan Nichols and Joaquin Cortiella from the University of Texas Medical Branch at Galveston, managed to bioengineer the first human lungs and now their work has progressed to the point of transplanting the lungs into pigs. Cortiella says […]

New lung cell type discovered

Lungs (stock illustration). Credit: © Mopic / Fotolia Lungs (stock illustration). Credit: © Mopic / Fotolia Close In separate studies published online in Nature on Aug. 1, two independent research teams report the discovery of a new, rare type of cell in the human airway. These cells appear to be the primary source of activity […]

New nano-optic endoscopes offer high-resolution imaging at extended depth of focus

The diagnosis of diseases based in internal organs often relies on biopsy samples collected from affected regions. But collecting such samples is highly error-prone due to the inability of current endoscopic imaging techniques to accurately visualize sites of disease. The conventional optical elements in catheters used to access hard-to-reach areas of the body, such as […]