Category: pulmonary

These are extracellular vesicles under the electron microscope Credit: Helmholtz Zentrum München These are extracellular vesicles under the electron microscope Credit: Helmholtz Zentrum München Close Idiopathic pulmonary fibrosis (IPF) is an incurable lung disease of unknown origin with limited treatment options. Research suggests that the signaling molecule WNT5A plays a key role in the pathogenic […]

Idiopathic pulmonary fibrosis (IPF) is an incurable lung disease of unknown origin with limited treatment options. Research suggests that the signaling molecule WNT5A plays a key role in the pathogenic process. Now a group of scientists from Helmholtz Zentrum München working with colleagues from the University of Denver have taken a further step towards uncovering […]

Hereditary pulmonary alveolar proteinosis (herPAP) is a rare disease characterized by the slow build-up of lipo-protein material in the lungs due to the failure of highly specialized cells called macrophages, which usually eat away this material from the pulmonary air-space. On August 9 in the journal Stem Cell Reports, researchers in Germany demonstrate that a […]

Scientists at Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago took a major step toward developing a new treatment for pulmonary arterial hypertension (PAH), a severe lung disease with a five-year survival rate of 50 percent. They identified a drug with a positive safety profile that inhibits a […]

Researchers have successfully transplanted bioengineered lungs into pigs, without any complications arising. © crystal light/Shutterstock.com In 2014, Joan Nichols and Joaquin Cortiella from the University of Texas Medical Branch at Galveston, managed to bioengineer the first human lungs and now their work has progressed to the point of transplanting the lungs into pigs. Cortiella says […]

In separate studies published online in Nature on Aug. 1, two independent research teams report the discovery of a new, rare type of cell in the human airway. These cells appear to be the primary source of activity of the CFTR gene, mutations to which cause cystic fibrosis, a multiorgan disease that affects more than […]

Lungs (stock illustration). Credit: © Mopic / Fotolia Lungs (stock illustration). Credit: © Mopic / Fotolia Close In separate studies published online in Nature on Aug. 1, two independent research teams report the discovery of a new, rare type of cell in the human airway. These cells appear to be the primary source of activity […]

The diagnosis of diseases based in internal organs often relies on biopsy samples collected from affected regions. But collecting such samples is highly error-prone due to the inability of current endoscopic imaging techniques to accurately visualize sites of disease. The conventional optical elements in catheters used to access hard-to-reach areas of the body, such as […]

Caption This is a scanning electron micrograph image of a portion of a fabricated metalens. Credit: Harvard SEAS Caption This is a scanning electron micrograph image of a portion of a fabricated metalens. Credit: Harvard SEAS Close The diagnosis of diseases based in internal organs often relies on biopsy samples collected from affected regions. But […]

The figure shows two views, frontal and lateral, of the image obtained by CT of the lungs of a mouse with fibrosis (grey areas) before and after receiving nano-therapy directed at senescent cells. Credit: Guillem Garaulet and Francisca Mulero, CNIO. The figure shows two views, frontal and lateral, of the image obtained by CT of […]