AAA doses first patients in two clinical studies with PSMA-R2 for prostate cancer

Advanced Accelerator Applications S.A. (AAA), a Novartis company and leader in nuclear medicine theragnostics, today announced that the first patients have been dosed in two Phase I/II clinical studies of radiolabeled PSMA-R2, a urea-based ligand of Prostate-Specific Membrane Antigen (PSMA), which is commonly expressed on prostate cancer cells. The PROter study is an open-label, multi-center, […]

‘Best Ideas’ to Come to Baltimore for Fifth Annual Metastatic Breast Cancer Conference

A gathering of clinicians, researchers, advocates and patients will share information and shed light on the need for improved focus and funding for metastatic and stage IV breast cancer. Attendees listen to a presentation at the 2017 conference. Credit: Baylor College of Medicine The fifth annual Metastatic Breast Cancer Conference invites participants from around the […]

Unusual cell-to-cell communication in glioblastoma promotes aggressiveness and therapy resistance

A surprising form of cell-to-cell communication in glioblastoma promotes global changes in recipient cells, including aggressiveness, motility, and resistance to radiation or chemotherapy. Paradoxically, the sending cells in this signaling are glioblastoma cells that are undergoing programed cell death, or apoptosis, according to research by a team at institutes in the United States, Russia and […]

Opening up a drug delivery route: Discovery of a new vehicle peptide

In the field of anticancer therapeutics, cationic antimicrobial peptides (AMPs) have gained prominence because of their cytotoxic and anticancer activity in drug-resistant cancer cells. Peptides are compounds consisting of two or more amino acids linked in a chain. A membrane impermeable proapoptotic domain (PAD) peptide [KLAKLAK]2 is known to be an antimicrobial agent and to […]

The GW Cancer Center expands bone marrow transplant and cell therapies

The George Washington University (GW) Cancer Center is pleased to welcome a team of internationally-recognized experts who together will lead the expanded Bone Marrow Transplant and Cell Therapies Program. John Barrett, MD, will lead this expansion at the GW Cancer Center, including the translation of clinical research efforts into novel immune cell-based therapies. He will […]

UC Riverside researcher receives grants to advance cancer, ALS research

Maurizio Pellecchia, who holds the Daniel Hays Chair in Cancer Research at the University of California, Riverside, has received two grants to continue his research aimed at finding therapeutics for cancer, amyotrophic lateral sclerosis (ALS), and other neurodegenerative diseases. The first grant from the U.S.-Egypt Science and Technology Joint Fund of the National Academy of […]

WVU researchers increase colorectal cancer screening rates in West Virginia

In West Virginia, where colorectal cancer is the second-deadliest type of cancer, half of all colorectal cancers elude diagnosis until they have already grown beyond the colon. With Medicaid expansion, more West Virginians now have health insurance for cancer screening, yet many barriers to screening persist. West Virginia University researchers are working to improve screening […]