Category: cancer

Stiffer breast tissue creates an environment more prone to cancer by enabling the disease to interfere with the surrounding healthy cells, according to a recent study published in Biomaterials. Scientists studying tumor growth and metastasis at the University of Notre Dame fabricated a human tissue model to examine how cancer cells interact with connective tissue […]

Antibody Drug Conjugates (ADCs) are relatively new anti-cancer drugs. They consist of an antibody to which a cell-killing molecule (chemotherapy) is attached. Antibodies can recognize and bind to certain receptors (the ‘hands’ on the outside of a cell) in a very targeted way. The antibody in an ADC is designed to adhere exclusively to receptors […]

Researchers in China have discovered that an enzyme called UGT8 drives the progression of basal-like breast cancer, an aggressive form of the disease that is largely untreatable. But the study, which will be published May 4 in the Journal of Experimental Medicine, reveals that the widely used osteoporosis drug zoledronic acid inhibits UGT8 and prevents […]

Diets rich in nuts, such as walnuts, have been shown to play a role in heart health and in reducing colorectal cancer. According to a new study from the University of Illinois, the way walnuts impact the gut microbiome — the collection of trillions of microbes or bacteria in the gastrointestinal tract — may be […]

One major hallmark of cancer cells is their ability to adapt to stressful conditions such as nutrient deprivation. Rapidly growing tumor cells must compete for the ever-diminishing supply of nutrients in the surrounding environment to survive and proliferate. Targeting these adaptive mechanisms represents a promising approach for cancer therapeutics. Sanford Prebys Medical Discovery Institute (SBP) […]

Breakthrough research has unraveled the complex chemistry of Madagascar periwinkle. the plant produces the cancer-fighting compound vinblastine. Credit: Andrew Davis – John Innes Centre Breakthrough research has unraveled the complex chemistry of Madagascar periwinkle. the plant produces the cancer-fighting compound vinblastine. Credit: Andrew Davis – John Innes Centre Close Plant scientists have taken the crucial […]

Can we slow basal-like breast cancer? Osteoporosis drug offers hope Basal-like breast cancer affects women at a relatively young age and is challenging to treat. The discovery that a common drug for osteoporosis may halt its progress is welcome news. New research offers a potential avenue for the treatment of basal-like breast cancer. Basal-like breast […]

The University of Miami Miller School of Medicine’s Department of Otolaryngology-Head and Neck Surgery is one of eight otolaryngology training programs in the U.S. to receive the Ruth L. Kirschstein National Research Service Award Institutional Research Training Grant (T32) for interdisciplinary research training in otolaryngology. Research conducted under this grant is supported by the National […]

Esther Gomez, assistant professor of chemical engineering and biomedical engineering, Penn State, has received the National Science Foundation’s (NSF) prestigious Early Career (CAREER) award to better understand the mechanobiology of mesenchymal-epithelial transition (MET). MET is a cell differentiation process in which a cell transitions from a moving cell to a stationary cell. This transition is […]

FRIDAY, May 4, 2018 — Two anti-cancer drugs administered together have been approved by the U.S. Food and Drug Administration to treat an inherited form of thyroid cancer. Tafinlar (dabrafenib) and Mekinist (trametinib) combined have been approved to treat anaplastic thyroid cancer caused by an abnormal BRAF V600E gene, the agency said Friday in a […]